Child and Adolescent Multimodal Treatment Study (CAMS)

Comparing Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety

Walkup, J. T., Albano, A. M., Piacentini, J., Birmaher, B., Compton, S. N., Sherrill, J. T., Ginsburg, G. S., et al. (2008). Beneficial Effects of Psychological Treatment, Medication and their Combination. The New England Journal of Medicine, 359(26), 275

  • This study found that both psychological treatment (CBT) and medication (sertraline), as well as their combination, were effective in the reduction of anxiety in children and adolescents. CBT (59.7%) was as effective as medication (54.9%) and their combination (80.7%) was better than both combined by the end of treatment phase.

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